The MIF Polyclonal Antibody (CAB1391) is a crucial tool for researchers studying the macrophage migration inhibitory factor (MIF) protein. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal choice for experiments involving MIF detection and analysis.MIF is a pro-inflammatory cytokine that plays a key role in various biological processes, including immune responses, inflammation, and cell proliferation. By targeting the MIF protein, researchers can gain valuable insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for diseases like cancer, autoimmune disorders, and inflammatory conditions.
Validated for use in Western blot applications, the MIF Polyclonal Antibody enables precise and reliable detection of MIF in various cell types, making it an invaluable tool for immunology and cancer research studies. By understanding the function and regulation of MIF, researchers can further elucidate its role in disease pathogenesis and develop strategies for targeted interventions.
Product Name:
MIF Rabbit Polyclonal Antibody
SKU:
CAB1391
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human MIF (NP_002406.1).
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Purification Method:
Affinity purification
Gene ID:
4282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIF Rabbit pAb (CAB1391) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
