Mif Antibody (PACO64043)
- SKU:
- PACO64043
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Mif Antibody (PACO64043)
The MIF Polyclonal Antibody (PACO64043) is specifically designed for research involving MIF, a cytokine known for its role in immune regulation and inflammatory responses. The antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the MIF protein, this antibody allows for the detection and analysis of MIF in various cell types, making it an ideal tool for studies in immunology, inflammation, and infectious diseases.
MIF, or Macrophage Migration Inhibitory Factor, is a key player in the innate immune response and has been implicated in numerous diseases, including sepsis, rheumatoid arthritis, and cancer. Its ability to modulate inflammation and promote cell survival makes it a promising target for therapeutic intervention. Research using this antibody can help uncover the mechanisms by which MIF contributes to disease pathogenesis and may lead to the development of novel treatments targeting this cytokine.
| Antibody Name: | Mif Antibody (PACO64043) |
| Antibody SKU: | PACO64043 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Macrophage migration inhibitory factor protein (2-115AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse Liver tissue, Mouse Spleen tissue, Mouse kidney tissue, Mouse Brain tissue, Hela whole cell lysate. All lanes: Mif antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 13 kDa. Observed band size: 13 kDa. |
| Background: | Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity). |
| Synonyms: | Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Delayed early response protein 6) (DER6) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase), Mif |
| UniProt Protein Function: | Function: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity |
| UniProt Protein Details: | Catalytic activity: Keto-phenylpyruvate = enol-phenylpyruvate.1 PublicationManual assertion based on experiment in:Ref.12 |
| UniProt Code: | P34884 |
| NCBI GenInfo Identifier: | 6754696 |
| NCBI Gene ID: | 17319 |
| NCBI Accession: | NP_034928.1 |
| UniProt Related Accession: | P34884 |
| Molecular Weight: | 12,504 Da |
| NCBI Full Name: | macrophage migration inhibitory factor |
| NCBI Synonym Full Names: | macrophage migration inhibitory factor |
| NCBI Official Symbol: | Mif  |
| NCBI Official Synonym Symbols: | GIF; Glif  |
| NCBI Protein Information: | macrophage migration inhibitory factor; DER6; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; glycosylation-inhibiting factor; delayed early response protein 6 |
| UniProt Protein Name: | Macrophage migration inhibitory factor |
| UniProt Synonym Protein Names: | Delayed early response protein 6; DER6; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase |
| Protein Family: | Macrophage migration inhibitory factor |
| UniProt Gene Name: | Mif  |
| UniProt Entry Name: | MIF_MOUSE |
| ELISA Kits |
| Mouse MIF ELISA Kit |
| Mouse MIF (Macrophage Migration Inhibitory Factor) CLIA Kit (MOES00431) |
| Mouse Macrophage migration inhibitory factor (Mif) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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