Mif Antibody, FITC conjugated (PACO64045)
- SKU:
- PACO64045
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- FITC
Description
Mif Antibody, FITC conjugated (PACO64045)
The MIF Antibody (FITC Conjugated) is a valuable tool for researchers studying Macrophage Migration Inhibitory Factor (MIF), a key cytokine involved in inflammation, immunity, and cell proliferation. This polyclonal antibody is conjugated with FITC for easy detection using fluorescence microscopy or flow cytometry techniques. With high reactivity towards human samples, this antibody is ideal for immunofluorescence staining and flow cytometry analysis, allowing for precise localization and quantification of MIF within various cell types. Researchers in fields such as immunology, cancer biology, and infectious diseases can utilize this antibody to investigate the role of MIF in disease progression and immune responses.
Given the critical functions of MIF in inflammatory processes and immune regulation, understanding its expression and activity is crucial for developing targeted therapies for conditions such as autoimmune disorders, cancer, and infectious diseases. The MIF Antibody (FITC Conjugated) provides a reliable tool for investigating the role of MIF in these pathologies and may contribute to the development of novel treatment strategies in the future.
| Antibody Name: | Mif Antibody?FITC conjugated (PACO64045) |
| Antibody SKU: | PACO64045 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Macrophage migration inhibitory factor protein (2-115AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | FITC |
| Background: | Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity). |
| Synonyms: | Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Delayed early response protein 6) (DER6) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase), Mif |
| UniProt Protein Function: | Function: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity |
| UniProt Protein Details: | Catalytic activity: Keto-phenylpyruvate = enol-phenylpyruvate.1 PublicationManual assertion based on experiment in:Ref.12 |
| UniProt Code: | P34884 |
| NCBI GenInfo Identifier: | 6754696 |
| NCBI Gene ID: | 17319 |
| NCBI Accession: | NP_034928.1 |
| UniProt Related Accession: | P34884 |
| Molecular Weight: | 12,504 Da |
| NCBI Full Name: | macrophage migration inhibitory factor |
| NCBI Synonym Full Names: | macrophage migration inhibitory factor |
| NCBI Official Symbol: | Mif  |
| NCBI Official Synonym Symbols: | GIF; Glif  |
| NCBI Protein Information: | macrophage migration inhibitory factor; DER6; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; glycosylation-inhibiting factor; delayed early response protein 6 |
| UniProt Protein Name: | Macrophage migration inhibitory factor |
| UniProt Synonym Protein Names: | Delayed early response protein 6; DER6; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase |
| Protein Family: | Macrophage migration inhibitory factor |
| UniProt Gene Name: | Mif  |
| UniProt Entry Name: | MIF_MOUSE |
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