Mif Antibody, Biotin conjugated (PACO64046)
- SKU:
- PACO64046
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Biotin
Description
Mif Antibody, Biotin conjugated (PACO64046)
The MIF Antibody Biotin Conjugated (PAC064046) is a valuable tool for researchers studying Macrophage Migration Inhibitory Factor (MIF), a pro-inflammatory cytokine involved in immune responses and inflammatory diseases. This antibody, conjugated with biotin for enhanced detection, is raised in rabbits and is highly reactive with human samples.The MIF antibody is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry, enabling researchers to analyze MIF expression and localization in different cell types and tissues.
Its specificity to MIF protein makes it a reliable tool for investigating the role of MIF in diseases such as cancer, rheumatoid arthritis, and sepsis.By targeting MIF, researchers can gain insights into its function in immune regulation and inflammation, paving the way for the development of novel therapies that target MIF signaling pathways. The MIF Antibody Biotin Conjugated is an essential reagent for in-depth studies on MIF biology and its potential as a therapeutic target in inflammatory disorders.
| Antibody Name: | Mif Antibody?Biotin conjugated (PACO64046) |
| Antibody SKU: | PACO64046 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Macrophage migration inhibitory factor protein (2-115AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Biotin |
| Background: | Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity). |
| Synonyms: | Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Delayed early response protein 6) (DER6) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase), Mif |
| UniProt Protein Function: | Function: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity |
| UniProt Protein Details: | Catalytic activity: Keto-phenylpyruvate = enol-phenylpyruvate.1 PublicationManual assertion based on experiment in:Ref.12 |
| UniProt Code: | P34884 |
| NCBI GenInfo Identifier: | 6754696 |
| NCBI Gene ID: | 17319 |
| NCBI Accession: | NP_034928.1 |
| UniProt Related Accession: | P34884 |
| Molecular Weight: | 12,504 Da |
| NCBI Full Name: | macrophage migration inhibitory factor |
| NCBI Synonym Full Names: | macrophage migration inhibitory factor |
| NCBI Official Symbol: | Mif  |
| NCBI Official Synonym Symbols: | GIF; Glif  |
| NCBI Protein Information: | macrophage migration inhibitory factor; DER6; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; glycosylation-inhibiting factor; delayed early response protein 6 |
| UniProt Protein Name: | Macrophage migration inhibitory factor |
| UniProt Synonym Protein Names: | Delayed early response protein 6; DER6; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase |
| Protein Family: | Macrophage migration inhibitory factor |
| UniProt Gene Name: | Mif  |
| UniProt Entry Name: | MIF_MOUSE |
Related Products
Mif Antibody, FITC conjugated (PACO64045)
CBY1 Antibody, Biotin conjugated (PACO64090)
RHBDF2 Antibody, Biotin conjugated (PACO64917)
GFRAL Antibody, Biotin conjugated (PACO36909)
BETVIA Antibody, Biotin conjugated (PACO65160)
Fgf2 Antibody, Biotin conjugated (PACO64022)
GRK7 Antibody, Biotin conjugated (PACO64118)
ANKRD42 Antibody, Biotin conjugated (PACO64106)
