The MIER2 Polyclonal Antibody (PACO16690) is specifically designed for research involving MIER2, a protein known for its role in transcriptional regulation, chromatin remodeling, and cell differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.MIER2, also referred to as mesoderm induction early response 1, is a key player in gene expression regulation and cellular processes such as development and differentiation. Its involvement in chromatin remodeling and transcriptional regulation makes it a significant target for studies in fields like developmental biology, cancer research, and stem cell research.
The MIER2 antibody enables detection and analysis of this protein in different cell types, providing valuable insights into its functions and potential implications in various disease processes.Understanding the role of MIER2 in transcriptional regulation and cellular differentiation is crucial for advancements in research areas such as gene therapy, regenerative medicine, and understanding the molecular mechanisms underlying developmental disorders. The MIER2 Polyclonal Antibody offers researchers a reliable tool for investigating the functions and mechanisms of this protein, contributing to the progress of scientific investigations in diverse biological contexts.
Antibody Name:
MIER2 Antibody (PACO16690)
Antibody SKU:
PACO16690
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human MIER2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16690(MIER2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
MIER2(mesoderm induction early response 1, family member 2), also known as Mi-er2 or KIAA1193, is a protein that in humans is encoded by the MIER2 gene. It is a transcriptional repressor.
Synonyms:
mesoderm induction early response 1, family member 2
UniProt Protein Function:
MIER2: Transcriptional repressor.
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleus
Molecular Function:DNA binding; chromatin binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
