The MICU2 Polyclonal Antibody (CAB12198) is a valuable tool for researchers studying the MICU2 protein, a key regulator of calcium uptake in mitochondria. This antibody, produced from rabbit serum, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MICU2 protein, this antibody allows for the detection and analysis of MICU2 levels in various cell types, making it an essential component for studies in cell biology and mitochondrial function.MICU2 plays a crucial role in maintaining calcium homeostasis in mitochondria, which is essential for proper energy production and cell survival.
Dysregulation of MICU2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. Research into the function of MICU2 is key to understanding these diseases and developing targeted therapies to restore calcium balance and mitochondrial function. Overall, the MICU2 Polyclonal Antibody is a valuable tool for researchers investigating the role of MICU2 in cellular processes and disease pathways. Its specificity and reliability make it a trusted resource for advancing our understanding of mitochondrial calcium regulation.
Product Name:
MICU2 Rabbit Polyclonal Antibody
SKU:
CAB12198
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MICU2 (NP_689939.1).
Sequence:
TNET GYQE AIVK EPEI N
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
EFHA1; 1110008L20Rik; MICU2
Positive Sample:
293T,U-87MG
Conjugate:
Unconjugated
Cellular Localization:
Mitochondrion intermembrane space.
Calculated MW:
50kDa
Observed MW:
45kDa
Enables protein heterodimerization activity. Involved in calcium import into the mitochondrion and negative regulation of mitochondrial calcium ion concentration. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Part of uniplex complex.
Purification Method:
Affinity purification
Gene ID:
221154
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MICU2 Rabbit pAb (CAB12198) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
