MICU1 Polyclonal Antibody (CAB21948)
- SKU:
- CAB21948
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | MICU1 Polyclonal Antibody |
SKU: | CAB21948 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 105-255 of human MICU1 (NP_001182447.1). |
Sequence: | GFRD RKVM EYEN RIRA YSTP DKIF RYFA TLKV ISEP GEAE VFMT PEDF VRSI TPNE KQPE HLGL DQYI IKRF DGKK ISQE REKF ADEG SIFY TLGE CGLI SFSD YIFL TTVL STPQ RNFE IAFK MFDL NGDG EVDM EEFE QVQS IIRS QTS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | CALC; EFHA3; MPXPS; CBARA1; ara CALC; MICU1 |
Positive Sample: | OVCAR3,A-431,293T |
Conjugate: | Unconjugated |
Cellular Localization: | mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membrane, mitochondrion |
Calculated MW: | 54kDa |
Observed MW: | 46kDa |
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 10367 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |