The MIB2 Polyclonal Antibody (CAB17829) is a powerful research tool designed for the study of MIB2, a protein known for its role in regulating cell division and cell cycle progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the MIB2 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for researchers in the fields of cell biology and cancer research.MIB2, also known as Mindbomb E3 Ubiquitin Protein Ligase 2, is a key player in controlling the timing and fidelity of cell division, making it a crucial target for studying cellular processes and potential therapeutic interventions.
With its involvement in cell cycle regulation, MIB2 is of particular interest in cancer research, where dysregulation of cell division can lead to uncontrolled cell growth and tumor formation. By understanding the mechanisms by which MIB2 operates, researchers can uncover new insights into the development and progression of various diseases, paving the way for innovative treatment strategies.
Product Name:
MIB2 Rabbit Polyclonal Antibody
SKU:
CAB17829
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-580 of human MIB2 (NP_001164158.1).
The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion.
Purification Method:
Affinity purification
Gene ID:
142678
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIB2 Rabbit pAb (CAB17829) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
