MIB1/DIP1 Rabbit Polyclonal Antibody (CAB8588)
- SKU:
- CAB8588
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | MIB1/DIP1 Rabbit Polyclonal Antibody |
SKU: | CAB8588 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 560-860 of human MIB1/DIP1 (NP_065825.1). |
Sequence: | DSEG DTPL HDAI SKKR DDIL AVLL EAGA DVTI TNNN GFNA LHHA ALRG NPSA MRVL LSKL PRPW IVDE KKDD GYTA LHLA ALNN HVEV AELL VHQG NANL DIQN VNQQ TALH LAVE RQHT QIVR LLVR AGAK LDIQ DKDG DTPL HEAL RHHT LSQL RQLQ DMQD VGKV DAAW EPSK NTLI MGLG TQGA EKKS AASI ACFL AANG ADLS IRNK KGQS PLDL CPDP NLCK ALAK CHKE KVSG QVGS RSPS MISN DSET LEEC MVCS DMKR DTLF GPCG HIAT CSLC SPRV KKCL ICKE QVQS R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2; MIB1/DIP1 |
Positive Sample: | U-87MG,A-549,HepG2,Mouse stomach,Mouse lung,Mouse kidney ,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, centriolar satellite, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 110kDa |
Observed MW: | 110kDa |
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
Purification Method: | Affinity purification |
Gene ID: | 57534 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |