The MIA Polyclonal Antibody (PACO53446) is a crucial tool for researchers studying melanoma inhibitory activity (MIA), a protein associated with malignant melanoma and other cancers. This antibody, produced in rabbits, is highly specific to human MIA and is validated for use in Western blot and immunohistochemistry applications.MIA, a secreted protein, is involved in cell growth, invasion, and metastasis in various cancer types, making it a potential biomarker for cancer diagnosis and prognosis. By targeting MIA with this antibody, researchers can gain insights into the role of MIA in cancer development and progression, as well as explore potential therapeutic interventions targeting this protein.
With its high reactivity and specificity to human MIA, the MIA Polyclonal Antibody is an essential tool for studies in oncology and cancer research. Whether investigating MIA expression in tumor samples or exploring MIA's potential as a therapeutic target, this antibody provides reliable and accurate results for advancing our understanding of cancer biology.
Antibody Name:
MIA Antibody (PACO53446)
Antibody SKU:
PACO53446
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Melanoma-derived growth regulatory protein (87-124AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO53446 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate tissue using PACO53446 at dilution of 1:100.
Background:
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Synonyms:
Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein), MIA
UniProt Protein Function:
MIA: Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. Belongs to the MIA/OTOR family.Protein type: Cell adhesion; Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 19q13.2Cellular Component: extracellular spaceMolecular Function: growth factor activityBiological Process: cell proliferation
