The MIA Monoclonal Antibody (PACO07406) is a powerful tool for researchers studying Melanoma Inhibitory Activity (MIA), a protein marker linked to melanoma progression and metastasis. This mouse-derived antibody is highly specific to MIA in human samples and is ideal for use in immunohistochemistry and ELISA applications. By targeting the MIA protein, this antibody enables precise detection and analysis in various tissue samples, offering valuable insights into the role of MIA in cancer development and progression.
MIA, a secreted protein expressed by melanoma cells, is known to promote tumor growth, invasion, and resistance to therapy. Its upregulation is associated with advanced stages of melanoma, making it a promising biomarker for prognosis and therapeutic targeting. The MIA Monoclonal Antibody provides researchers with a reliable tool to investigate the role of MIA in melanoma biology, aiding in the development of targeted therapies for this aggressive form of skin cancer.
Antibody Name:
MIA Antibody (PACO07406)
Antibody SKU:
PACO07406
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:10000-1:20000, IHC-p:1:50-1:300
Species Reactivity:
Human
Immunogen:
Synthetic peptide from human protein at AA range: 90-131
Form:
Liquid
Storage Buffer:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded Human-heart, antibody was diluted at 1:100.
Immunohistochemical analysis of paraffin-embedded Human-heart, antibody was diluted at 1:100.
Synonyms:
Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein)
UniProt Protein Function:
MIA: Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. Belongs to the MIA/OTOR family.Protein type: Cell adhesion; Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 19q13.2Cellular Component: extracellular spaceMolecular Function: growth factor activityBiological Process: cell proliferation
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