The MGST2 Polyclonal Antibody (CAB16400) is a vital tool for researchers studying MGST2, an enzyme involved in lipid metabolism and cellular responses to oxidative stress. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for Western blot applications. By binding to the MGST2 protein, researchers can accurately detect and analyze its expression in various cell types, providing valuable insights in the fields of biochemistry and cell biology.
MGST2, also known as microsomal glutathione S-transferase 2, plays a crucial role in maintaining cellular redox balance and protecting cells from oxidative damage. The enzyme's involvement in lipid peroxidation processes makes it a potential target for investigating metabolic disorders, neurodegenerative diseases, and cancer. Understanding the functions of MGST2 is essential for designing therapeutic strategies aimed at modulating lipid metabolism and oxidative stress in pathological conditions.
Product Name:
MGST2 Rabbit Polyclonal Antibody
SKU:
CAB16400
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human MGST2 (NP_002404.1).
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Purification Method:
Affinity purification
Gene ID:
4258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MGST2 Rabbit pAb (CAB16400) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
