The MGLL Polyclonal Antibody (CAB6654) is a valuable tool for researchers studying MGLL, a key enzyme involved in lipid metabolism and signaling pathways. This antibody, generated in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for Western blot applications.MGLL, also known as monoacylglycerol lipase, plays a crucial role in the hydrolysis of monoacylglycerols, which are important intermediates in lipid metabolism. Dysregulation of MGLL has been linked to various diseases such as cancer, neurological disorders, and metabolic syndromes, making it a promising target for therapeutic intervention.
By utilizing the MGLL Polyclonal Antibody, researchers can effectively detect and quantify MGLL protein levels in different cell types and tissues, enabling a better understanding of its role in disease pathogenesis. This antibody is a valuable tool for studies in cancer biology, neuroscience, and metabolism research, ultimately leading to the development of novel treatment strategies targeting MGLL-related conditions.
Product Name:
MGLL Rabbit Polyclonal Antibody
SKU:
CAB6654
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 11-313 of human MGLL (NP_009214.1).
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
11343
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MGLL Rabbit pAb (CAB6654) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
