The MGAT4A Polyclonal Antibody (CAB15401) is a powerful tool for researchers studying MGAT4A, a critical enzyme involved in the synthesis of complex N-glycans in the Golgi apparatus. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it ideal for use in Western blot applications. By binding specifically to the MGAT4A protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a valuable asset for studies in glycosylation pathways and related diseases.MGAT4A is known for its role in the glycosylation of proteins, playing a key part in cellular processes such as protein folding, trafficking, and signaling.
Dysregulation of MGAT4A has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders. Research into the functions and mechanisms of MGAT4A is vital for understanding these disease processes and potentially developing targeted therapies in the future.Overall, the MGAT4A Polyclonal Antibody is a valuable tool for researchers investigating the intricate workings of glycosylation pathways and their implications in human health and disease. Its specificity and sensitivity make it an essential component in studies aiming to unravel the complexities of MGAT4A function in various biological contexts.
Product Name:
MGAT4A Rabbit Polyclonal Antibody
SKU:
CAB15401
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-100 of human MGAT4A (NP_036346.1).
Golgi apparatus membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
62kDa
Observed MW:
61kDa
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
Purification Method:
Affinity purification
Gene ID:
11320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MGAT4A Rabbit pAb (CAB15401) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
