The MGAT3 Monoclonal Antibody is a vital tool for researchers studying the MGAT3 protein, an enzyme involved in the biosynthesis of complex N-linked glycans. This antibody, generated using cutting-edge technology, exhibits high specificity and sensitivity for detecting MGAT3 in human samples, making it ideal for various research applications such as Western blotting and immunofluorescence.MGAT3 plays a crucial role in the modification of glycoproteins, impacting processes like cell-cell interactions, cell signaling, and immune responses.
Dysregulation of MGAT3 expression has been linked to various diseases, including cancer and inflammatory disorders, making it a promising target for therapeutic interventions. By using the MGAT3 Monoclonal Antibody, researchers can gain insights into the function and regulation of MGAT3, ultimately advancing our understanding of disease mechanisms and potential treatment strategies.
Product Name:
MGAT3 Monoclonal Antibody
SKU:
CAB24347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 381-480 of human MGAT3 (NP_002400.3).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
61kDa
Observed MW:
61kDa
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
4248
Clone Number:
ARC60778
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MGAT3 Rabbit mAb (CAB24347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): mouse skeletal muscle.Exposure time: 45s.
