The MFSD2A Polyclonal Antibody (CAB18288) is a valuable tool for researchers studying MFSD2A, a cell surface protein involved in the regulation of nutrient transport across the blood-brain barrier. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications.MFSD2A, also known as major facilitator superfamily domain-containing protein 2A, plays a crucial role in maintaining brain function by facilitating the transport of essential nutrients like docosahexaenoic acid (DHA) into the brain.
Dysregulation of MFSD2A has been implicated in neurological disorders such as Alzheimer's disease and epilepsy, making it a promising target for therapeutic intervention.By utilizing the MFSD2A Polyclonal Antibody, researchers can effectively detect and analyze MFSD2A protein expression in various cell types, providing valuable insights into its function in brain health and disease. This antibody is a valuable tool for studies in neuroscience, neurology, and drug development aimed at targeting MFSD2A for the treatment of neurological conditions.
Product Name:
Mfsd2a Rabbit Polyclonal Antibody
SKU:
CAB18288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-245 of mouse Mfsd2a (NP_083938.2).
Enables fatty acid transmembrane transporter activity; lysophosphatidylcholine flippase activity; and lysophospholipid:sodium symporter activity. Involved in central nervous system development; lipid transport; and transcytosis. Acts upstream of or within several processes, including photoreceptor cell development; regulation of lipid metabolic process; and retina development in camera-type eye. Located in plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (major facilitator superfamily domain containing 2A).
Purification Method:
Affinity purification
Gene ID:
76574
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Mfsd2a Rabbit pAb (CAB18288) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
