Mitofusin 2 Rabbit Polyclonal Antibody (CAB13606)
- SKU:
- CAB13606
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Mitofusin 2 Rabbit Polyclonal Antibody |
SKU: | CAB13606 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of mouse Mitofusin 2 (NP_573464.2). |
Sequence: | TTEE QVLD VKGY LSKV RGIS EVLA RRHM KVAF FGRT SNGK STVI NAML WDKV LPSG IGHT TNCF LRVG GTDG HEAF LLTE GSEE KKSV KTVN QLAH ALHQ DEQL HAGS MVSV MWPN SKCP LLKD DLVL MDSP GIDV TTEL DSWI DKFC LDAD VFVL VANS ESTL MQTE KQFF HKVS ERLS RPNI FILN NRW |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | Fzo; D630023P19Rik; Mitofusin 2 |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion outer membrane, Multi-pass membrane protein. |
Calculated MW: | 68kDa/86kDa |
Observed MW: | 80kDa |
Predicted to enable several functions, including GTP binding activity; GTPase activity; and enzyme binding activity. Involved in mitochondrial fusion; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; and positive regulation of cold-induced thermogenesis. Acts upstream of or within blastocyst formation and camera-type eye morphogenesis. Located in microtubule cytoskeleton and mitochondrion. Is expressed in several structures, including brain; early conceptus; eye; heart; and oocyte. Used to study Charcot-Marie-Tooth disease type 2A2A. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease type 2A2A; Charcot-Marie-Tooth disease type 2A2B; and Charcot-Marie-Tooth disease type 6. Orthologous to human MFN2 (mitofusin 2).
Purification Method: | Affinity purification |
Gene ID: | 170731 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |