Mitofusin 2 Rabbit Polyclonal Antibody (CAB12771)
- SKU:
- CAB12771
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Mitofusin 2 Rabbit Polyclonal Antibody |
SKU: | CAB12771 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 70-260 of human Mitofusin 2 (NP_055689.1). |
Sequence: | TTEE QVLD VKGY LSKV RGIS EVLA RRHM KVAF FGRT SNGK STVI NAML WDKV LPSG IGHT TNCF LRVE GTDG HEAF LLTE GSEE KRSA KTVN QLAH ALHQ DKQL HAGS LVSV MWPN SKCP LLKD DLVL MDSP GIDV TTEL DSWI DKFC LDAD VFVL VANS ESTL MQTE KHFF HKVS ERLS RPNI FILN NRW |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | HSG; MARF; CMT2A; CPRP1; CMT2A2; HMSN6A; CMT2A2A; CMT2A2B; Mitofusin 2 |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion outer membrane, Multi-pass membrane protein. |
Calculated MW: | 86kDa |
Observed MW: | 80kDa |
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Purification Method: | Affinity purification |
Gene ID: | 9927 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |