The MFN1 Polyclonal Antibody (CAB15474) is a vital tool for researchers studying mitochondrial dynamics and fusion. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. It specifically binds to the MFN1 protein, allowing for accurate detection and analysis in various cell types.MFN1, also known as mitofusin-1, is a key player in mitochondrial fusion and regulation of mitochondrial morphology. Dysregulation of MFN1 has been linked to various diseases, including neurodegenerative disorders and metabolic diseases.
Research into the function of MFN1 is crucial for understanding the mechanisms underlying these conditions and developing potential therapeutic interventions.With its high specificity and sensitivity, the MFN1 Polyclonal Antibody is a valuable tool for investigating the role of MFN1 in mitochondrial dynamics and its implications for human health. Researchers in the fields of cell biology, biochemistry, and neuroscience will find this antibody essential for their studies.
Product Name:
MFN1 Rabbit Polyclonal Antibody
SKU:
CAB15474
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse MFN1 (NP_077162.2).
Predicted to enable GTPase activity and identical protein binding activity. Involved in mitochondrial fusion and positive regulation of mitochondrial membrane potential. Located in mitochondrion. Is expressed in embryo; heart; and placenta. Orthologous to human MFN1 (mitofusin 1).
Purification Method:
Affinity purification
Gene ID:
67414
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MFN1 antibody (CAB15474) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
