The MFF Rabbit Monoclonal Antibody (CAB8700) is a valuable tool for researchers studying the mitochondrial outer membrane protein MFF (mitochondrial fission factor), which plays a crucial role in mitochondrial dynamics and cellular homeostasis. This antibody, generated using rabbit monoclonal technology, demonstrates high specificity and sensitivity in detecting MFF in various cellular contexts.MFF is involved in regulating mitochondrial fission, a process essential for maintaining mitochondrial quality and function. Dysregulation of MFF has been linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
By targeting MFF with this monoclonal antibody, researchers can investigate the role of MFF in mitochondrial dynamics, cellular metabolism, and disease pathology.Validated for use in immunofluorescence, immunohistochemistry, and other experimental techniques, the MFF Rabbit Monoclonal Antibody provides researchers with a reliable tool for visualizing and analyzing MFF expression and localization in different cell types and tissues. Its high specificity and sensitivity make it a valuable asset in studies aimed at understanding the role of MFF in cellular physiology and disease progression.
Product Name:
MFF Rabbit Monoclonal Antibody
SKU:
CAB8700
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MFF (Q9GZY8).
Cytoplasmic vesicle, Mitochondrion outer membrane, Peroxisome, Single-pass type IV membrane protein, secretory vesicle, synaptic vesicle.
Calculated MW:
38kDa
Observed MW:
35kDa
This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
56947
Clone Number:
ARC1243
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MFF Rabbit mAb (CAB8700) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
