The MFF Polyclonal Antibody (CAB4874) from Assay Genie is a valuable tool for researchers studying the Midline-1 mitochondrial dynamics regulator protein (MFF). This antibody, generated in rabbits, is highly specific for human samples and is ideal for use in Western blot applications. By targeting the MFF protein, this antibody allows for the detection and analysis of MFF in various cell types, making it an essential component for studies in mitochondrial dynamics and related fields.MFF is a key player in regulating mitochondrial fission, a process essential for maintaining mitochondrial integrity and function. Dysregulation of mitochondrial dynamics has been linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
By targeting MFF, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.Overall, the MFF Polyclonal Antibody (CAB4874) offers researchers a reliable tool for investigating the function of MFF in health and disease. Its high specificity and sensitivity make it a valuable asset for those studying mitochondrial dynamics and seeking to advance our understanding of related pathological processes.
Product Name:
MFF Rabbit Polyclonal Antibody
SKU:
CAB4874
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MFF (NP_064579.3).
Cytoplasmic vesicle, Mitochondrion outer membrane, Peroxisome, Single-pass type IV membrane protein, secretory vesicle, synaptic vesicle.
Calculated MW:
38kDa
Observed MW:
25-35kDa
This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
56947
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat heart, using MFF Rabbit pAb (CAB4874) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
