MFAP4 Antibody (PACO57856)
- SKU:
- PACO57856
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MFAP4 Antibody (PACO57856)
The MFAP4 Polyclonal Antibody (PAC057856) is a valuable tool for research involving the Microfibril Associated Protein 4 (MFAP4), a protein involved in extracellular matrix formation and regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in a variety of applications, including Western blot and immunohistochemistry.MFAP4 is known for its role in modulating tissue remodeling and fibrosis, making it a key player in various pathological processes, including cardiovascular diseases and fibrotic disorders. By targeting MFAP4 with this antibody, researchers can investigate its expression and function in different cell types and tissues, providing insights into its involvement in disease progression and potential therapeutic interventions.
The MFAP4 Polyclonal Antibody is an essential tool for studies in molecular biology, pathology, and drug development, offering researchers a reliable method for detecting and analyzing MFAP4 protein levels in experimental samples. With its high specificity and sensitivity, this antibody is ideal for investigating the complex role of MFAP4 in various disease processes and identifying new targets for therapeutic intervention.
| Antibody Name: | MFAP4 Antibody (PACO57856) |
| Antibody SKU: | PACO57856 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Microfibril-associated glycoprotein 4 protein (100-191AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO57856 diluted at 1:300 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO57856 diluted at 1:300 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance. |
| Synonyms: | Microfibril-associated glycoprotein 4, MFAP4 |
| UniProt Protein Function: | MFAP4: Could be involved in calcium-dependent cell adhesion or intercellular interactions. MFAP4 is deleted in the Smith-Magenis syndrome (SMS). |
| UniProt Protein Details: | Protein type:Secreted; Cell adhesion; Secreted, signal peptide; Calcium-binding Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: extracellular matrix; microfibril; extracellular region Molecular Function:protein binding Biological Process: elastic fiber assembly; extracellular matrix organization and biogenesis; UV protection; fibril organization and biogenesis; cell adhesion |
| NCBI Summary: | This gene encodes a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
| UniProt Code: | P55083 |
| NCBI GenInfo Identifier: | 2506403 |
| NCBI Gene ID: | 4239 |
| NCBI Accession: | P55083.2 |
| UniProt Secondary Accession: | P55083,Q6P680, A8KAJ1, A8MVM2, B4E317, |
| UniProt Related Accession: | P55083 |
| Molecular Weight: | 28,648 Da |
| NCBI Full Name: | Microfibril-associated glycoprotein 4 |
| NCBI Synonym Full Names: | microfibrillar-associated protein 4 |
| NCBI Official Symbol: | MFAP4Â Â |
| NCBI Protein Information: | microfibril-associated glycoprotein 4 |
| UniProt Protein Name: | Microfibril-associated glycoprotein 4 |
| Protein Family: | Microfibril-associated glycoprotein |
| UniProt Gene Name: | MFAP4Â Â |
| UniProt Entry Name: | MFAP4_HUMAN |
| Antibodies | ELISA Kits |
| MFAP4 Antibody (PACO10469) | Human MFAP4 ELISA Kit |
| Human MFAP4 (Microfibrillar Associated Protein 4) CLIA Kit (HUES00390) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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