null

MFAP4 Antibody (PACO10469)

SKU:
PACO10469
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

MFAP4 Antibody (PACO10469)

The MFAP4 Polyclonal Antibody (PAC010469) is specifically designed for research involving MFAP4, a protein associated with extracellular matrix remodeling and fibrosis. The antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in various immunoassays, including Western blotting and immunohistochemistry.MFAP4, also known as microfibril-associated glycoprotein 4, plays a key role in regulating the structure and function of elastic fibers in connective tissues. Its involvement in fibrotic processes makes it a potential target for studying conditions such as pulmonary fibrosis, liver cirrhosis, and cardiovascular diseases.

By using the MFAP4 antibody, researchers can investigate the expression and localization of MFAP4 in different tissues and cell types, providing valuable insights into the mechanisms underlying fibrosis-related pathologies.Understanding the role of MFAP4 in tissue remodeling and fibrotic diseases is essential for developing novel therapeutic strategies aimed at modulating its activity and preventing or treating fibrosis. The MFAP4 Polyclonal Antibody offers a reliable tool for studying MFAP4 expression and function in various research contexts, contributing to advancements in the field of fibrosis research.

Antibody Name:MFAP4 Antibody (PACO10469)
Antibody SKU:PACO10469
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human MFAP4
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:microfibrillar-associated protein 4;
UniProt Protein Function:MFAP4: Could be involved in calcium-dependent cell adhesion or intercellular interactions. MFAP4 is deleted in the Smith-Magenis syndrome (SMS).
UniProt Protein Details:

Protein type:Secreted; Cell adhesion; Secreted, signal peptide; Calcium-binding

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: extracellular matrix; microfibril; extracellular region

Molecular Function:protein binding

Biological Process: elastic fiber assembly; extracellular matrix organization and biogenesis; UV protection; fibril organization and biogenesis; cell adhesion

NCBI Summary:This gene encodes a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
UniProt Code:P55083
NCBI GenInfo Identifier:2506403
NCBI Gene ID:4239
NCBI Accession:P55083.2
UniProt Secondary Accession:P55083,Q6P680, A8KAJ1, A8MVM2, B4E317,
UniProt Related Accession:P55083
Molecular Weight:28,648 Da
NCBI Full Name:Microfibril-associated glycoprotein 4
NCBI Synonym Full Names:microfibrillar-associated protein 4
NCBI Official Symbol:MFAP4  
NCBI Protein Information:microfibril-associated glycoprotein 4
UniProt Protein Name:Microfibril-associated glycoprotein 4
Protein Family:Microfibril-associated glycoprotein
UniProt Gene Name:MFAP4  
UniProt Entry Name:MFAP4_HUMAN

Related Products