The MFAP3L Polyclonal Antibody (PAC028218) is a valuable tool for research involving MFAP3L, a protein associated with extracellular matrix organization and regulation of cell adhesion. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications. By binding to the MFAP3L protein, researchers can accurately detect and analyze its expression in various cell types, facilitating studies in cell biology and tissue remodeling processes.MFAP3L, also known as microfibril-associated protein 3-like, plays a crucial role in maintaining the structural integrity of the extracellular matrix and influencing cell adhesion dynamics.
Its function in these processes suggests potential implications in diseases such as fibrosis, cardiovascular disorders, and tissue remodeling-related conditions. Investigating the role of MFAP3L can provide insights into the underlying mechanisms of these diseases and potentially lead to the development of targeted therapies aimed at modulating extracellular matrix interactions.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO28218 at dilution of 1:100.
Immunofluorescent analysis of A549 cells using PACO28218 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human testis tissue using PACO28218 at dilution of 1:100.
Background:
cytoplasm, nucleus, plasma membrane
Synonyms:
Microfibrillar-associated protein 3-like (Testis development protein NYD-SP9), MFAP3L, KIAA0626
UniProt Protein Function:
MFAP3L: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 4q32.3Cellular Component: cytoplasm; integral to membrane; nucleus; plasma membraneMolecular Function: protein binding
