null

Anti-METTL5 Antibody (CAB9217)

SKU:
CAB9217
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Anti-METTL5 Antibody (CAB9217)

The Mettl5 Polyclonal Antibody (CAB9217) is specially designed for research involving Mettl5, a key enzyme involved in RNA modification. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the Mettl5 protein, allowing for accurate detection and analysis in a variety of cell types, making it a valuable tool for studies related to RNA modification and gene expression regulation.Mettl5 is known for its important role in transferring methyl groups to RNA molecules, leading to modifications that impact gene expression and cellular functions. Understanding the function and regulation of Mettl5 is essential for unraveling the complexities of RNA modification processes and their implications in various biological pathways.

Research involving Mettl5 may offer insights into diseases related to dysregulated gene expression, such as cancer, neurological disorders, and developmental abnormalities.Overall, the Mettl5 Polyclonal Antibody (CAB9217) is a reliable resource for researchers exploring the intricacies of RNA modification and its role in gene regulation. Its high specificity and sensitivity make it an essential tool for investigating the function and significance of Mettl5 in various biological contexts.

Antibody Name:Anti-METTL5 Antibody
Antibody SKU:CAB9217
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human METTL5 (NP_054887.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, Mouse liver, Mouse kidney, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human METTL5 (NP_054887.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKKV RLKE LESR LQQV DGFE KPKL LLEQ YPTR PHIA ACML YTIH NTYD DIEN KVVA DLGC GCGV LSIG TAML GAGL CVGF DIDE DALE IFNR NAEE FELT NIDM VQCD VCLL SNRM SKSF DTVI MNPP FGTK NNKG TDMA FLKT ALEM ARTA VYSL HKSS TREH VQKK AAEW KIKI DIIA ELRY DLPA SYKF HKKK SVDI EVDL IRFS F
Gene ID:29081
Uniprot:Q9NRN9
Cellular Location:
Calculated MW:23kDa
Observed MW:24kDa
Synonyms:METTL5, HSPC133
Background:
UniProt Protein Function:METTL5: Probable methyltransferase. Belongs to the methyltransferase superfamily. PrmA family.
UniProt Protein Details:

Protein type:EC 2.1.1.-; Methyltransferase

Chromosomal Location of Human Ortholog: 2q31.1

Molecular Function:methyltransferase activity; nucleic acid binding

Biological Process: methylation

UniProt Code:Q9NRN9
NCBI GenInfo Identifier:645912918
NCBI Gene ID:29081
NCBI Accession:NP_001280115.1
UniProt Secondary Accession:Q9NRN9,Q9NVX1, D3DPC9,
UniProt Related Accession:Q9NRN9
Molecular Weight:Calculated MW: 24kDa
NCBI Full Name:methyltransferase-like protein 5
NCBI Synonym Full Names:methyltransferase like 5
NCBI Official Symbol:METTL5  
NCBI Official Synonym Symbols:HSPC133  
NCBI Protein Information:methyltransferase-like protein 5
UniProt Protein Name:Methyltransferase-like protein 5
Protein Family:Methyltransferase-like protein
UniProt Gene Name:METTL5  
UniProt Entry Name:METL5_HUMAN
Anti-METTL5 Polyclonal Antibody (CAB9217)Western blot analysis of extracts of various cell lines, using METTL5 antibody (CAB9217) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 8s.

Related Products