The Mettl4 Monoclonal Antibody from Assay Genie (ABM10012) is a valuable tool for researchers studying the Mettl4 protein, a key regulator of mRNA methylation and gene expression. This monoclonal antibody, produced using hybridoma technology, is highly specific to Mettl4 and has been validated for use in immunofluorescence and immunohistochemistry applications. Mettl4 is a member of the methyltransferase family, known for its role in modulating RNA methylation and influencing cellular processes such as mRNA stability, translation, and protein synthesis. Dysregulation of Mettl4 has been linked to various diseases, including cancer, neurological disorders, and metabolic conditions.
By utilizing the Mettl4 Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of Mettl4 in different cell types and tissues, facilitating studies in molecular biology, epigenetics, and disease mechanisms. Its high specificity and sensitivity make it an essential reagent for investigating the role of Mettl4 in health and disease, ultimately paving the way for potential therapeutic interventions targeting this important protein.
Product Name:
METTL4 Monoclonal Antibody
SKU:
CAB23539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant protein of human METTL4.
Tested Applications:
IHC-PELISA
Recommended Dilution:
IHC-P,1:50 - 1:200
Synonyms:
HsT661; METTL4
Conjugate:
Unconjugated
Cellular Localization:
Nucleus, Cytoplasm
Calculated MW:
54kDa
Observed MW:
Refer to figures
Enables RNA methyltransferase activity and site-specific DNA-methyltransferase (adenine-specific) activity. Involved in nucleic acid metabolic process; regulation of RNA metabolic process; and regulation of mitochondrial DNA replication. Located in cytosol; mitochondrial matrix; and nucleus.
Purification Method:
Affinity purification
Gene ID:
64863
Clone Number:
ARC59459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human kidney using METTL4 Rabbit mAb (CAB23539) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
