The METTL20 Polyclonal Antibody (CAB7152) is a valuable tool for researchers investigating METTL20, a key enzyme involved in the methylation of RNA molecules. This antibody, developed using rabbit immunization, has high specificity for METTL20 in human samples and is suitable for use in Western blot applications. By binding to the METTL20 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential component in studies on RNA methylation and its role in cellular processes.METTL20 is a crucial player in the regulation of RNA methylation, a dynamic process that impacts gene expression and protein synthesis.
Dysregulation of RNA methylation has been linked to various diseases, including cancer and neurological disorders, making METTL20 a promising target for therapeutic interventions. Research on METTL20 is vital for understanding its mechanisms of action and potential implications in disease pathogenesis, paving the way for the development of novel treatment strategies aimed at targeting RNA methylation pathways.
Product Name:
METTL20 Rabbit Polyclonal Antibody
SKU:
CAB7152
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 105-262 of human METTL20 (NP_001129335.1).
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of electron transfer activity; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase; and peptidyl-lysine trimethylation. Located in mitochondrial matrix. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
254013
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse heart, using METTL20 antibody (CAB7152) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
