The Mettl16 Polyclonal Antibody (CAB15894) is a valuable tool for researchers studying Mettl16, an enzyme known for its role in regulating RNA modifications. This antibody, produced in rabbits, is highly specific to Mettl16 in human samples and has been validated for use in Western blot applications.Mettl16 is a methyltransferase enzyme that plays a crucial role in the methylation of RNA, particularly in the modification of transfer RNA (tRNA). Dysregulation of Mettl16 has been linked to various diseases, including cancer and neurological disorders.
By targeting Mettl16 with this polyclonal antibody, researchers can investigate its function and potential as a therapeutic target.The antibody binds specifically to Mettl16, allowing for the detection and analysis of this enzyme in different cell types. Its high reactivity and specificity make it an essential tool for studies in RNA biology, epigenetics, and disease mechanisms. By understanding the role of Mettl16, researchers can pave the way for novel treatments and interventions in various disease contexts.
Product Name:
METTL16 Rabbit Polyclonal Antibody
SKU:
CAB15894
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 263-562 of human METTL16 (NP_076991.3).
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
METT10D; METTL16
Positive Sample:
Hep G2
Conjugate:
Unconjugated
Cellular Localization:
cytoplasm, nucleus
Calculated MW:
64kDa
Observed MW:
70kDa
Enables RNA binding activity and RNA methyltransferase activity. Involved in RNA modification and regulation of mRNA metabolic process. Located in cytoplasm and nucleus.
Purification Method:
Affinity purification
Gene ID:
79066
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Hep G2 cells using METTL16 Rabbit pAb(CAB15894) at 1:900 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:30s.
