The Mettl13 Polyclonal Antibody (CAB7111) is a valuable tool for researchers studying Mettl13, a protein involved in the regulation of RNA metabolism and gene expression. This antibody, produced using rabbit immunizations, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Mettl13 protein, researchers can easily detect and analyze its expression in various cell types, making it a crucial asset for studies in molecular biology and cancer research.Mettl13 plays a crucial role in the modification of RNA molecules, impacting processes like mRNA stability and translation efficiency.
Understanding the function of Mettl13 is essential for unraveling its significance in diseases such as cancer and neurological disorders, where dysregulation of RNA metabolism can have profound effects on cellular behavior. By using the Mettl13 Polyclonal Antibody, researchers can gain valuable insights into the role of Mettl13 in various biological pathways, paving the way for the development of targeted therapies and precision medicine approaches.
Product Name:
METTL13 Rabbit Polyclonal Antibody
SKU:
CAB7111
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3).
Predicted to enable methyltransferase activity. Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleus.
Purification Method:
Affinity purification
Gene ID:
51603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using METTL13 antibody (CAB7111) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
