The Mettl13 Polyclonal Antibody (CAB12582) is a versatile tool for researchers studying Mettl13, a protein involved in epigenetic regulation and RNA modification. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the Mettl13 protein, this antibody allows for the detection and analysis of Mettl13 expression in various cell types, making it an essential resource for studies in molecular biology and cancer research.Mettl13 plays a crucial role in the post-transcriptional modification of RNA, impacting processes such as mRNA stability and translation.
Its involvement in epigenetic regulation suggests its potential implications in gene expression and cellular function. Research on Mettl13 can provide valuable insights into the molecular mechanisms underlying various diseases, including cancer and neurodevelopmental disorders. By elucidating the functions of Mettl13, researchers can uncover novel therapeutic targets and strategies for treating these conditions.
Product Name:
METTL13 Rabbit Polyclonal Antibody
SKU:
CAB12582
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 430-699 of human METTL13 (NP_057019.3).
Predicted to enable methyltransferase activity. Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleus.
Purification Method:
Affinity purification
Gene ID:
51603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of MCF7 cells, using METTL13 antibody (CAB12582) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
