The MetaP2 Polyclonal Antibody (CAB5962) is a valuable tool for researchers studying MetaP2, a protein involved in lipid metabolism and energy regulation. This antibody, produced in rabbits, is highly sensitive and specific for detecting MetaP2 in human samples, making it ideal for use in Western blot applications.MetaP2 plays a crucial role in lipid droplet formation and breakdown, as well as in regulating energy balance in cells. By targeting MetaP2 with this antibody, researchers can gain insights into how this protein contributes to metabolic processes and potentially uncover new therapeutic targets for metabolic disorders like obesity and diabetes.
With its high reactivity and specificity, the MetaP2 Polyclonal Antibody is a reliable tool for studies in metabolism, cell biology, and metabolic diseases. Its ability to detect MetaP2 in various cell types makes it a versatile resource for researchers looking to deepen their understanding of lipid metabolism and energy regulation. Overall, the MetaP2 Polyclonal Antibody is a valuable asset for research in the fields of metabolism, cell biology, and metabolic diseases, helping to advance our understanding of how MetaP2 influences lipid metabolism and energy regulation.
Product Name:
METAP2 Rabbit Polyclonal Antibody
SKU:
CAB5962
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human METAP2 (NP_006829.1).
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10988
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using METAP2 antibody (CAB5962) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
