The MEST Polyclonal Antibody (CAB6931) is a crucial tool for researchers studying MEST, a protein involved in cell proliferation and differentiation. This antibody, generated in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the MEST protein, this antibody enables the detection and analysis of MEST expression levels in various cell types, making it an invaluable resource for studies in developmental biology and cancer research.
MEST, also known as mesoderm-specific transcript, plays a key role in regulating cell growth and differentiation, making it a potential target for therapeutic interventions in diseases such as cancer. Understanding the function of MEST is essential for uncovering its potential as a biomarker or therapeutic target in various pathologies. By utilizing the MEST Polyclonal Antibody, researchers can gain valuable insights into the role of MEST in cellular processes and disease progression.
Product Name:
MEST Rabbit Polyclonal Antibody
SKU:
CAB6931
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 146-335 of human MEST (NP_002393.2).
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
Purification Method:
Affinity purification
Gene ID:
4232
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using MEST antibody (CAB6931) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
