MSLN Rabbit Polyclonal Antibody (CAB6183)
- SKU:
- CAB6183
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MSLN Rabbit Polyclonal Antibody |
SKU: | CAB6183 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 296-606 of human Mesothelin (NP_037536.2). |
Sequence: | EVEK TACP SGKK AREI DESL IFYK KWEL EACV DAAL LATQ MDRV NAIP FTYE QLDV LKHK LDEL YPQG YPES VIQH LGYL FLKM SPED IRKW NVTS LETL KALL EVNK GHEM SPQA PRRP LPQV ATLI DRFV KGRG QLDK DTLD TLTA FYPG YLCS LSPE ELSS VPPS SIWA VRPQ DLDT CDPR QLDV LYPK ARLA FQNM NGSE YFVK IQSF LGGA PTED LKAL SQQN VSMD LATF MKLR TDAV LPLT VAEV QKLL GPHV EGLK AEER HRPV RDWI LRQR QDDL DTLG LGLQ GGIP NGYL VLDL SMQE ALS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MPF; SMRP; Mesothelin |
Positive Sample: | OVCAR3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Golgi apparatus, Lipid-anchor, Secreted. |
Calculated MW: | 69kDa |
Observed MW: | 45kDa |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 10232 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |