NF2 Rabbit Polyclonal Antibody (CAB2456)
- SKU:
- CAB2456
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | NF2 Rabbit Polyclonal Antibody |
SKU: | CAB2456 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-595 of human NF2 (NP_000259.1). |
Sequence: | PKTF TVRI VTMD AEME FNCE MKWK GKDL FDLV CRTL GLRE TWFF GLQY TIKD TVAW LKMD KKVL DHDV SKEE PVTF HFLA KFYP ENAE EELV QEIT QHLF FLQV KKQI LDEK IYCP PEAS VLLA SYAV QAKY GDYD PSVH KRGF LAQE ELLP KRVI NLYQ MTPE MWEE RITA WYAE HRGR ARDE AEME YLKI AQDL EMYG VNYF AIRN KKGT ELLL GVDA LGLH IYDP ENRL TPKI SFPW NEIR NISY SDKE FTIK PLDK KIDV FKFN SSKL RVNK LILQ LCIG NHDL FMRR RKAD SLEV QQMK AQAR EEKA RKQM ERQR LARE KQMR EEAE RTRD ELER RLLQ MKEE ATMA NEAL MRSE ETAD LLAE KAQI TEEE AKLL AQKA AEAE QEMQ RIKA TAIR TEEE KRLM EQKV LEAE VLAL KMAE ESER RAKE ADQL KQDL QEAR EAER RAKQ KLLE IATK PTYP PMNP IPAP LPPD IPSF NLIG DSLS FDFK DTDM KRLS MEIE KEKV EYME KSKH LQEQ LNEL KTEI EALK LKER ETAL DILH NENS DRGG SSKH NTIK KLTL QSAK SRVA FFEE L |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ACN; SCH; BANF; merlin-1; NF2 |
Positive Sample: | U-251MG,Mouse brain,Mouse testis,PC-12,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Cytoplasmic granule, Cytoplasmic side, Nucleus, Nucleus, Peripheral membrane protein, cytoskeleton, filopodium membrane, perinuclear region, ruffle membrane. |
Calculated MW: | 70kDa |
Observed MW: | 73kDa |
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein's function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.
Purification Method: | Affinity purification |
Gene ID: | 4771 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |