MEOX2 Antibody (PACO06649)
- SKU:
- PACO06649
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MEOX2 Antibody (PACO06649)
The MEOX2 Polyclonal Antibody (PACO06649) is a valuable tool for researchers studying the MEOX2 protein, a transcription factor involved in various biological processes, including development and cell differentiation. This antibody, produced in rabbits, has a high reactivity with human samples and is suitable for use in Western blot applications. By targeting the MEOX2 protein, this antibody allows for the detection and analysis of MEOX2 expression in different cell types, making it an essential component for studies in developmental biology and cancer research.
MEOX2, also known as GAX, plays a crucial role in regulating gene expression and controlling cell fate decisions. Its involvement in developmental pathways and its impact on cell behavior make it a promising target for research into various diseases, such as cancer and developmental disorders. Understanding the function of MEOX2 is essential for uncovering its potential therapeutic implications in these contexts and advancing our knowledge of cellular processes.
| Antibody Name: | MEOX2 Antibody (PACO06649) |
| Antibody SKU: | PACO06649 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human MOX-2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of RAT-MUSCLE cells using MOX-2 Polyclonal Antibody. |
 | Western Blot analysis of COLO205 cells using MOX-2 Polyclonal Antibody. |
| Synonyms: | MEOX2; GAX; MOX2; Homeobox protein MOX-2; Growth arrest-specific homeobox; Mesenchyme homeobox 2 |
| UniProt Protein Function: | MEOX2: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 7p22.1-p21.3 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; sequence-specific DNA binding; transcription factor activity Biological Process: blood circulation; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50222 |
| NCBI GenInfo Identifier: | 93141286 |
| NCBI Gene ID: | 4223 |
| NCBI Accession: | P50222.2 |
| UniProt Secondary Accession: | P50222,O75263, Q9UPL6, B2R8I7, |
| UniProt Related Accession: | P50222 |
| Molecular Weight: | 33,594 Da |
| NCBI Full Name: | Homeobox protein MOX-2 |
| NCBI Synonym Full Names: | mesenchyme homeobox 2 |
| NCBI Official Symbol: | MEOX2Â Â |
| NCBI Official Synonym Symbols: | GAX; MOX2Â Â |
| NCBI Protein Information: | homeobox protein MOX-2 |
| UniProt Protein Name: | Homeobox protein MOX-2 |
| UniProt Synonym Protein Names: | Growth arrest-specific homeobox; Mesenchyme homeobox 2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | MEOX2Â Â |
| UniProt Entry Name: | MEOX2_HUMAN |
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