The MEN1 Polyclonal Antibody (CAB15290) is a valuable tool for researchers studying the MEN1 gene, which is known to be associated with multiple endocrine neoplasia type 1. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MEN1 protein, this antibody enables the detection and analysis of MEN1 expression in various cell types, making it ideal for investigations in endocrine disorders and cancer research.
The MEN1 gene plays a critical role in regulating cell growth and division, making it a key player in the development of endocrine tumors. Research on the MEN1 gene and its protein product is essential for gaining insights into the underlying mechanisms driving tumorigenesis in multiple endocrine neoplasia type 1. By understanding the functions of MEN1, researchers can potentially identify new therapeutic targets for treating endocrine tumors and related disorders.
Product Name:
Menin Rabbit Polyclonal Antibody
SKU:
CAB15290
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 266-615 of human Menin (NP_000235.2).
This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones.
Purification Method:
Affinity purification
Gene ID:
4221
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Menin Rabbit pAb (CAB15290) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
