The Melanotransferrin Polyclonal Antibody (CAB6653) is a valuable tool for research involving melanotransferrin, a protein involved in various biological processes such as iron transport and cell signaling. This high-quality antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.Melanotransferrin, also known as MTF or CD228, is a glycoprotein that plays a role in iron metabolism and cellular growth regulation. It has been implicated in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases, making it a target of interest in research aimed at understanding the mechanisms underlying these conditions.
This antibody allows for the detection and analysis of melanotransferrin expression in different cell types, providing researchers with valuable insights into its function and potential implications in various diseases. By studying melanotransferrin, researchers can uncover new therapeutic targets and develop innovative approaches for the treatment of a range of medical conditions.
Product Name:
MFI2 Rabbit Polyclonal Antibody
SKU:
CAB6653
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1).
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.
Purification Method:
Affinity purification
Gene ID:
4241
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MFI2 antibody (CAB6653) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
