The MELK Polyclonal Antibody (CAB10794) is a valuable tool for researchers studying MELK, a protein kinase implicated in cell cycle regulation and cancer progression. This antibody, developed in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the MELK protein, this antibody enables precise detection and analysis in various cell types, making it an essential resource for studies in cancer biology and therapeutic development.
MELK, also known as maternal embryonic leucine zipper kinase, plays a crucial role in cancer cell proliferation and survival, making it a promising target for cancer therapy. Its involvement in multiple signaling pathways and cellular processes highlights its potential as a biomarker for cancer diagnosis and prognosis. By understanding the function and regulation of MELK, researchers can pave the way for innovative treatment strategies and personalized medicine approaches in oncology.
Product Name:
MELK Rabbit Polyclonal Antibody
SKU:
CAB10794
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 412-651 of human MELK (NP_055606.1).
Enables calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Involved in apoptotic process; cell population proliferation; and protein autophosphorylation. Located in cell cortex and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
9833
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MELK Rabbit pAb (CAB10794) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
