MLPH Rabbit Polyclonal Antibody (CAB6656)
- SKU:
- CAB6656
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MLPH Rabbit Polyclonal Antibody |
SKU: | CAB6656 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-600 of human MLPH (NP_077006.1). |
Sequence: | EQLP LQYL ADVD TSDE ESIR AHVM ASHH SKRR GRAS SESQ IFEL NKHI SAVE CLLT YLEN TVVP PLAK GLGA GVRT EADV EEEA LRRK LEEL TSNV SDQE TSSE EEEA KDEK AEPN RDKS VGPL PQAD PEVG TAAH QTNR QEKS PQDP GDPV QYNR TTDE ELSE LEDR VAVT ASEV QQAE SEVS DIES RIAA LRAA GLTV KPSG KPRR KSNL PIFL PRVA GKLG KRPE DPNA DPSS EAKA MAVP YLLR RKFS NSLK SQGK DDDS FDRK SVYR GSLT QRNP NARK GMAS HTFA KPVV AHQS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SLAC2-A; MLPH |
Positive Sample: | Mouse stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 66kDa |
Observed MW: | 75kDa |
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 79083 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |