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MEK7 Polyclonal Antibody (CAB23058)

SKU:
CAB23058
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
€129
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MEK7 Polyclonal Antibody
SKU:CAB23058
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:Recombinant protein of human MEK7.
Sequence:DPPD PTKP DYDI RADV WSLG ISLV ELAT GQFP YKNC KTDF EVLT KVLQ EEPP LLPG HMGF SGDF QSFV KDCL TKDH RKRP KYNK LLEH SFIK RYET LEVD VASW FKDV MAKT ESPR TSGV LSQP HLPF FR
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IF/ICC,1:20 - 1:200
Synonyms:MEK; MKK7; JNKK2; MEK 7; MAPKK7; PRKMK7; SAPKK4; SAPKK-4; MEK7
Positive Sample:Rat skeletal muscle
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:47kDa
Observed MW:47kDa

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:5609
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of Rat skeletal muscle, using MEK7 antibody (CAB23058) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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