MEK1 Rabbit Monoclonal Antibody (CAB19565)
- SKU:
- CAB19565
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MEK1 Rabbit Monoclonal Antibody |
SKU: | CAB19565 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEK1 (Q02750). |
Sequence: | MPKK KPTP IQLN PAPD GSAV NGTS SAET NLEA LQKK LEEL ELDE QQRK RLEA FLTQ KQKV GELK DDDF EKIS ELGA GNGG VVFK VSHK PSGL VMAR KLIH |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | MEL; CFC3; MEK1; MKK1; MAPKK1; PRKMK1 |
Positive Sample: | HeLa,HepG2,A-431,Mouse brain,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center, spindle pole body. |
Calculated MW: | 43kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Purification Method: | Affinity purification |
Gene ID: | 5604 |
Clone Number: | ARC0044 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |