The MEK1/MEK2 Rabbit Monoclonal Antibody (CAB4868) is a crucial tool for research involving the MEK1 and MEK2 proteins, key components of the MAPK signaling pathway. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting MEK1 and MEK2 in human samples, making it ideal for use in Western blot applications.The MEK1/MEK2 antibody enables researchers to study the activity and expression of these important signaling molecules in various cell types, providing valuable insights into cellular signaling pathways involved in processes such as cell proliferation, differentiation, and survival.
By targeting MEK1 and MEK2, researchers can gain a better understanding of the mechanisms underlying diseases such as cancer, where dysregulation of the MAPK pathway is common.Overall, the MEK1/MEK2 Rabbit Monoclonal Antibody (CAB4868) is a valuable tool for studying the MAPK signaling pathway and its role in cellular physiology and disease. Its high reactivity and reliability make it a trusted resource for researchers in fields such as cancer biology, cell signaling, and drug development.
Product Name:
MEK1/MEK2 Rabbit Monoclonal Antibody
SKU:
CAB4868
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MEK1/MEK2 (Q02750).
cytosol, early endosome, endoplasmic reticulum, focal adhesion, Golgi apparatus, late endosome, microtubule organizing center, mitochondrion, nucleus, plasma membrane
Calculated MW:
44kDa
Observed MW:
42kDa
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
Purification Method:
Affinity purification
Gene ID:
5604/5605
Clone Number:
ARC0292
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MEK1/MEK2 antibody (CAB4868) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
