The MEIS1 Polyclonal Antibody (CAB18273) is an essential tool for researchers studying the MEIS1 protein, a transcription factor involved in developmental processes, specifically in the regulation of hematopoiesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the MEIS1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in developmental biology and hematological disorders.
MEIS1, a key player in regulating gene expression during development, is crucial for the proper formation and function of blood cells. Dysregulation of MEIS1 has been linked to various hematopoietic malignancies and developmental abnormalities. Understanding the function of MEIS1 is essential for uncovering its role in disease pathogenesis and potential therapeutic targets. The MEIS1 Polyclonal Antibody provides researchers with a valuable tool for investigating the intricate mechanisms underlying hematopoiesis and related disorders.
Product Name:
MEIS1 Rabbit Polyclonal Antibody
SKU:
CAB18273
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-390 of human MEIS1 (NP_002389.1).
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.
Purification Method:
Affinity purification
Gene ID:
4211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MEIS1 Rabbit pAb (CAB18273) at 1:900 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 20s.
