The MEI4 Polyclonal Antibody (PAC047862) is a valuable tool for researchers studying MEI4, a protein involved in meiotic recombination and DNA repair processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MEI4 protein, researchers can accurately detect and analyze MEI4 expression in various cell types, making it an essential tool for studies in genetics and reproductive biology.MEI4 is essential for proper meiotic chromosome segregation and recombination, making it a key player in ensuring genetic diversity and fertility. Dysregulation of MEI4 has been linked to infertility and chromosomal abnormalities, highlighting its importance in reproductive health and genetic stability.
By understanding the function of MEI4, researchers can uncover potential targets for treating infertility and genetic disorders related to meiotic dysfunction.Overall, the MEI4 Polyclonal Antibody is a valuable resource for researchers investigating the intricate processes of meiotic recombination and DNA repair, offering insights into the role of MEI4 in reproductive health and genetic stability. Its high specificity and reactivity make it a reliable tool for advancing research in genetics and reproductive biology.
Antibody Name:
MEI4 Antibody (PACO47862)
Antibody SKU:
PACO47862
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Meiosis-specific protein MEI4-like protein (22-137AA)
Western Blot. Positive WB detected in: Mouse heart tissue. All lanes: MEI4 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa..
Background:
Required for meiotic DNA double-strand break formation.
Synonyms:
Meiosis-specific protein MEI4, MEI4
UniProt Protein Function:
MEI4: Required for meiotic DNA double-strand break formation. Belongs to the MEI4L family. Interacts with REC114-like protein C15orf60Chromosomal Location of Human Ortholog: -Cellular Component: lateral elementBiological Process: meiotic DNA double-strand break formation; oogenesis; spermatogenesis; synapsis
