The MEF2D Polyclonal Antibody (CAB16398) is a valuable tool for researchers studying the MEF2D protein, a transcription factor involved in various cellular processes, including muscle development, neuronal survival, and immune response regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting MEF2D in human samples, making it an optimal choice for Western blot applications.MEF2D is a key player in the regulation of gene expression and signal transduction pathways that influence cell differentiation, survival, and function. Its involvement in multiple physiological processes underscores its importance in developmental biology, neurobiology, and immunology research.
By targeting MEF2D, researchers can gain insights into its functional roles in normal and pathological conditions, such as neurodegenerative diseases, cardiovascular disorders, and cancer.The MEF2D Polyclonal Antibody provides a reliable means to investigate the expression and activity of MEF2D in various experimental settings, facilitating the exploration of its molecular mechanisms and potential therapeutic targets. With its proven performance and versatility, this antibody is a valuable asset for elucidating the complex functions of MEF2D in health and disease.
Product Name:
MEF2D Rabbit Polyclonal Antibody
SKU:
CAB16398
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 431-521 of human MEF2D (NP_005911.1).
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4209
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MEF2D Rabbit pAb (CAB16398) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
