The MEF2C Polyclonal Antibody (CAB2585) is a powerful tool for researchers studying MEF2C, a transcription factor essential for the development and function of various tissues, particularly the brain and heart. Produced in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications. By targeting the MEF2C protein, this antibody allows for the precise detection and analysis of MEF2C expression in a variety of cell types, making it ideal for investigations in neuroscience and cardiovascular research.MEF2C plays a crucial role in the regulation of gene expression involved in cell differentiation, proliferation, and survival, making it a key player in developmental processes and tissue homeostasis.
Dysregulation of MEF2C has been linked to various disorders, including neurodevelopmental disorders, cardiac diseases, and cancer. Therefore, studying the function of MEF2C is essential for gaining insights into these conditions and potentially identifying new therapeutic targets.Overall, the MEF2C Polyclonal Antibody (CAB2585) offers researchers a reliable tool for investigating the role of MEF2C in health and disease, paving the way for advancements in biomedical research and drug development.
Product Name:
MEF2C Rabbit Polyclonal Antibody
SKU:
CAB2585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 170-380 of human MEF2C (NP_002388.2).
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
4208
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MEF2C Rabbit pAb (CAB2585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
