The MEF2C Polyclonal Antibody (CAB12385) is a valuable tool for researchers studying MEF2C, a transcription factor that plays a critical role in various biological processes, including cell differentiation, proliferation, and survival. This antibody is raised in rabbits and is highly reactive with human samples, making it suitable for use in Western blot applications.MEF2C is known for its involvement in the development of multiple tissues and organs, making it a key player in embryonic development and tissue regeneration.
Dysregulation of MEF2C has been implicated in various diseases, including neurological disorders and cancer.By detecting and analyzing the MEF2C protein in different cell types, this antibody can shed light on the role of MEF2C in various physiological and pathological processes. Its versatility makes it an ideal tool for researchers in the fields of developmental biology, neuroscience, and oncology, providing valuable insights into the mechanisms underlying these complex biological processes.
Product Name:
MEF2C Rabbit Polyclonal Antibody
SKU:
CAB12385
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-380 of human MEF2C (NP_002388.2).
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
4208
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using MEF2C Rabbit pAb (CAB12385) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
