The MEF2B Polyclonal Antibody (CAB15987) is a valuable tool for researchers studying the MEF2B protein, which is a transcription factor that plays a crucial role in various cellular processes, including cell growth, differentiation, and apoptosis. This antibody, generated in rabbits, is highly specific and reacts strongly with human samples, making it an ideal choice for Western blot applications.MEF2B is a significant regulator of gene expression and is involved in several biological pathways, making it a highly relevant target for research in fields such as oncology, developmental biology, and stem cell research.
By using the MEF2B Polyclonal Antibody, researchers can effectively detect and analyze MEF2B protein levels in different cell types, allowing for a deeper understanding of its functions and potential implications in disease development and progression.Furthermore, studying the role of MEF2B may lead to the discovery of novel therapeutic targets for diseases like cancer, cardiovascular disorders, and neurodegenerative conditions. The MEF2B Polyclonal Antibody is a valuable tool for uncovering the mechanisms underlying these diseases and ultimately advancing the development of targeted therapies and treatments.
Product Name:
MEF2B Rabbit Polyclonal Antibody
SKU:
CAB15987
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEF2B (NP_005910.1).
The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207.
Purification Method:
Affinity purification
Gene ID:
100271849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using MEF2B Rabbit pAb (CAB15987) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.