The MEF2B Polyclonal Antibody (CAB15986) is a crucial tool for researchers studying MEF2B, a transcription factor involved in regulating gene expression and cell development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.MEF2B plays a vital role in various biological processes, including muscle development, neuronal differentiation, and immune response regulation. Dysregulation of MEF2B has been implicated in several diseases, including cancer and neurodegenerative disorders. By targeting MEF2B with this antibody, researchers can effectively study its expression and activity in different cell types, providing valuable insights into its function and potential therapeutic applications.
Furthermore, understanding the role of MEF2B in disease pathogenesis may lead to the development of novel treatment strategies that target this transcription factor, offering new opportunities for precision medicine and personalized therapies. Get your hands on the MEF2B Polyclonal Antibody (CAB15986) today and advance your research in the fields of molecular biology, cancer biology, and neurobiology.
Product Name:
MEF2B Rabbit Polyclonal Antibody
SKU:
CAB15986
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEF2B (NP_005910.1).
The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207.
Purification Method:
Affinity purification
Gene ID:
100271849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using MEF2B Rabbit pAb (CAB15986) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
