The MEF2A Polyclonal Antibody (CAB12059) is a valuable tool for research involving MEF2A, a transcription factor that plays a key role in regulating gene expression in various cellular processes. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MEF2A protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology, developmental biology, and cardiovascular research.MEF2A is known for its involvement in crucial biological processes such as cell differentiation, proliferation, and apoptosis. Its importance in regulating gene expression makes it a promising target for investigating diseases like cardiovascular disorders, neurological disorders, and cancer.
Understanding the functions of MEF2A can provide insights into the underlying mechanisms of these diseases and potentially lead to the development of novel therapeutic strategies.Overall, the MEF2A Polyclonal Antibody is a reliable tool for researchers looking to explore the role of MEF2A in various physiological and pathological conditions. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of gene regulation and uncovering potential therapeutic targets for a range of diseases.
Product Name:
MEF2A Rabbit Polyclonal Antibody
SKU:
CAB12059
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEF2A (NP_001124400.1).
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4205
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MEF2A Rabbit pAb (CAB12059) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
